The Birth History of Sildenafil.
Sildenafil was initially developed for the treatment of cardiovascular diseases, and researchers hope that sildenafil can achieve therapeutic goals by releasing the bioactive substance nitric oxide to relax cardiovascular smooth muscle.
However, clinical studies have shown that sildenafil has shown limited effectiveness in testing the treatment of hypertension and angina, far from meeting the expectations of researchers. This once disappointed the research team, but an abnormal phenomenon in the participant's report caught their attention: male patients participating in the clinical study were unwilling to hand over excess drugs after testing, and there was no clear reason. After investigation, researchers found that sildenafil greatly improved the erectile function of male subjects.
After obtaining permission from Pfizer's senior management, researchers conducted research on the effect of sildenafil on the smooth muscle of the corpus cavernosum of the penis and obtained market approval from the Federal Food and Drug Administration on March 27, 1998, making sildenafil one of the products that made Pfizer famous.
However, clinical studies have shown that sildenafil has shown limited effectiveness in testing the treatment of hypertension and angina, far from meeting the expectations of researchers. This once disappointed the research team, but an abnormal phenomenon in the participant's report caught their attention: male patients participating in the clinical study were unwilling to hand over excess drugs after testing, and there was no clear reason. After investigation, researchers found that sildenafil greatly improved the erectile function of male subjects.
After obtaining permission from Pfizer's senior management, researchers conducted research on the effect of sildenafil on the smooth muscle of the corpus cavernosum of the penis and obtained market approval from the Federal Food and Drug Administration on March 27, 1998, making sildenafil one of the products that made Pfizer famous.
