What do you do when you overdose on Vardenafil Hydrochloride?

In single-dose subjects, the maximum experimental dose was 120mg per day (inclusive). The highest trial dose (80mg daily) was well tolerated without any serious adverse drug reactions. The same results were confirmed in another clinical trial of 40mg vardenafil (once daily) for 4 weeks. When vardenafil was administered at a dose of 40mg twice daily, several cases of severe back pain were observed, but no muscular or neurotoxic effects were confirmed.

In case of overdose, symptomatic treatment should be given as needed. Because vardenafil binds to plasma proteins at a high rate and is not primarily cleared by urine, renal dialysis does not increase its clearance in the body.